When you need to connect using an email client that does not support Exchange use IMAP to keep email in sync and use POP3 to download emails to a backup server.

IMAP Settings

POP Settings

SMTP Settings

Server: outlook.office365.com

Port: 993

Encryption: SSL/TLS

Username: (email address)

Password: (password)

Server: outlook.office365.com

Port: 995

Encryption: SSL/TLS

Username: (email address)

Password: (password)

Server: smtp.office365.com

Port: 587

Encryption: STARTTLS

Username: (email address)

Password: (password)